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Our Publications

OUR PUBLICATIONS

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Freeman EW, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, Carpenter JS, Anderson GL, Larson JC, Ensrud KE, Reed SD, Newton KM, Sherman S, Sammel MD, LaCroix AZ. Efficacy of Escitalopram for Hot Flashes in Healthy Menopausal Women: A Randomized Controlled Trial. JAMA 2011;305(3):267-274. [PMCID: PMC3129746]

Joffe H, Guthrie KA, Larson J, Cohen LS, Carpenter JS, LaCroix AZ, Freeman EW. Relapse of vasomotor symptoms after discontinuation of the selective serotonin reuptake inhibitor Escitalopram: results from the Menopause Strategies: Finding Lasting Answers for Symptoms and Health Research Network. Menopause 2013;20(3):261-268. [PMCID: PMC3561495]

Newton KM, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD, Sherman S, Sammel MD, Kroenke K, Larson JC, LaCroix AZ. Methods for the design of vasomotor symptom trials: the Menopausal Strategies: Finding Lasting Answers to Symptoms and Health network. Menopause 2014;21(1):45-58. [PMCID: PMC3796184]

Carpenter JS, Newton KN, Sternfeld BS, Joffe H, Reed SD, Ensrud KE, Milata J. Laboratory and ambulatory evaluation of vasomotor symptom monitors from the Menopause Strategies Finding Lasting Answers for Symptoms and Health network. Menopause 2012;19(6):664-671. [PMCID: PMC3326209]

Carpenter JS, Guthrie KA, Larson JC, Freeman EW, Joffe H, Reed SD, Ensrud KE, LaCroix AZ. Effect of escitalopram on hot flash interference: a randomized, controlled trial. Fertil Steril 2012;97(6):1399-1404. [PMCID: PMC3367120]

Ensrud KE, Joffe H, Guthrie KA, Larson JC, Reed SD, Newton KM, Sternfeld B, LaCroix AZ, Landis CA, Woods NF, Freeman EW. Effect of escitalopram on insomnia symptoms and subjective sleep quality in healthy perimenopausal and postmenopausal women with hot flashes: a randomized controlled trial. Menopause 2012;19(8):848-855. [PMCID: PMC3382013]

Reed SD, Guthrie KA, Joffe H, Shifren JL, Seguin RA, Freeman EW. Sexual function in nondepressed women using escitalopram for vasomotor symptoms: a randomized controlled trial. Obstet Gynecol 2012;119(3):527-538. [PMCID: PMC3345186]

Otte JL, Rand KC, Landis C, Paudel M, Newton KM, Woods N, Carpenter JS. Confirmatory factor analysis of the Pittsburgh sleep quality index in women with hot flashes. Menopause 2015;22(11):1190-1196. [PMCID: PMC4624473]

LaCroix AZ, Freeman EW, Larson J, Carpenter JS, Joffe H, Reed SD, Newton KM, Seguin RA, Sternfeld B, Cohen L, Ensrud KE. Effects of escitalopram on menopause-specific quality of life and pain in healthy menopausal women with hot flashes: a randomized controlled trial. Maturitas 2012;73(4):361-368. [PMCID: PMC3645479]

Sternfeld BS, Guthrie KA, Ensrud KE, LaCroix AZ, Larson JC, Dunn AL, Anderson GL, Sequin RA, Carpenter JS, Newton KM, Reed SD, Freeman EW, Cohen LS, Joffe H, Roberts M, Caan BJ. Efficacy of exercise for menopausal symptoms: a randomized controlled trial. Menopause 2014;21(4):330-338. [PMCID: PMC3858421]

Cohen LS, Joffe H, Guthrie KA, Ensrud KE, Freeman MP, Carpenter JS, Learman LA, Newton KM, Reed SD, Manson JE, Sternfeld B, Caan BJ, Freeman EW, LaCroix AZ, Tinker LF, Booth-LaForce C, Larson JC, Anderson GL. Efficacy of Omega-3 for vasomotor symptoms treatment: a randomized controlled trial. Menopause 2014;21(4):347-354. [PMCID: PMC4072122]

Newton KM, Reed SD, Guthrie KA, Sherman KJ, Booth-LaForce C, Caan B, Sternfeld B, Carpenter JS, Learman LA, Freeman EW, Cohen LS, Joffe H, Anderson GL, Larson JC, Hunt JR, Ensrud KE, LaCroix AZ. Efficacy of yoga for vasomotor symptoms: a randomized controlled trial. Menopause 2014;21(4):339-346. [PMCID: PMC3871975]

Sternfeld B, LaCroix A, Caan BJ, Dunn AL, Newton KM, Reed SD, Guthrie KA, Booth-LaForce C, Sherman KJ, Cohen L, Freeman MP, Carpenter JS, Hunt JR, Roberts M, Ensrud KE. Design and methods of a multi-site, multi-behavioral treatment trial for menopausal symptoms: the MsFLASH experience. Contemp Clin Trials 2013;35:25–34. [PMCID: PMC3670607]

Reed SD, Guthrie KA, Newton KM, Anderson GL, Booth-LaForce C, Caan B, Carpenter JS, Cohen LS, Dunn AL, Ensrud KE, Freeman EW, Hunt JR, Joffe H, Larson JC, Learman LA, Rothenberg R, Seguin RA, Sherman KJ, Sternfeld BS, LaCroix AZ. Menopausal quality of life: RCT of yoga, exercise, and Omega-3 supplements. Am J Obstet Gynecol 2014;210(3):244.e1-244.e11. [PMCID: PMC3976276]

Carpenter JS, Woods NF, Otte JL, Guthrie KA, Hohensee C, Newton KM, Joffe H, Cohen L, Sternfeld BS, Lau RJ, Reed SD, LaCroix AZ. MsFLASH participants’ priorities for alleviating menopausal symptoms. Climacteric 2015;18(6):1-8. [PMCID: PMC4732703]

Carpenter JS, Reed SD, Guthrie KA, Larson JC, Newton KM, Lau RJ, Learman LA, Shifren JL. Using an FSDS-R item to screen for sexually related distress: a MsFLASH analysis. Sex Med 2015;3(1):7-13. [PMCID: PMC4380908]

Carpenter JS, Jones SMW, Studts CR, Heiman JR, Shifren JL, Reed SD, Newton KM, Guthrie KA, Larson JC, Cohen LS, Freeman EW, Lau RJ, Learman LA. Female Sexual Function Index Short Version: a MsFLASH response analysis. Arch Sex Behav 2016;45(8):1897-1905. [PMCID: PMC5053877]

Freeman EW, Ensrud K, Larson J, Guthrie KA, Carpenter J, Joffe H, Newton K, Sternfeld B, LaCroix AZ. Placebo improvement in pharmacologic treatment of menopausal hot flashes: time course, duration, and predictors. Psychosom Med 2015;77(2):167-175. [PMCID: PMC4333078]

Reed SD, Newton KM, Larson JC, Booth-LaForce C, Woods NF, Landis CA, Tolentino E, Carpenter JS, Freeman EW, Joffe H, Anawalt BD, Guthrie KA. Daily salivary cortisol patterns in midlife women with hot flashes. Clin Endocrinol (Oxf) 2016;84(5):672-679. [PMCID: PMC5106033]

Joffe H, Guthrie KA, LaCroix AZ, Reed SD, Ensrud KE, Manson JE, Newton KM, Freeman EW, Anderson GL, Larson JC, Hunt JR, Shifren J, Rexrode KM, Caan B, Sternfeld B, Carpenter JS, Cohen LS. Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine for vasomotor symptoms: a randomized clinical trial. JAMA Intern Med 2014;174(7):1058-1066. [PMCID: PMC4179877]

Otte JL, Bakoyannis G, Rand KL, Ensrud KE, Guthrie KA, Joffe H, McCurry SM, Newton KM, Carpenter JS. Confirmatory factor analysis of the Insomnia Severity Index (ISI) and invariance across race: a pooled analysis of MsFLASH data. Menopause 2019; 26(8):850-855. PMC6663566

Woods NF, Hohensee C, Carpenter JS, Cohen L, Ensrud K, Freeman EW, Guthrie KA, Joffe H, LaCroix AZ, Otte JL, Cochrane B. Symptom clusters among MsFLASH clinical trial participants. Menopause 2016;23(2):158-165. [PMCID: PMC4731298]

Mitchell CM, Srinivasan S, Zhan X, Wu MC, Reed SD, Guthrie KA, LaCroix AZ, Fiedler T, Munch M, Liu C, Hoffman NG, Blair IA, Newton K, Freeman E, Joffe H, Cohen L, Fredricks DN. Vaginal microbiota and genitourinary menopausal symptoms: a cross-sectional analysis. Menopause 2017;24(10):1160-1166. [PMCID: PMC5607086]

Guthrie KA, LaCroix AZ, Ensrud KE, Joffe H, Newton KM, Reed SD, Caan B, Carpenter JS, Cohen LS, Freeman EW, Larson JC, Manson JE, Rexrode K, Skaar TC, Sternfeld B, Anderson GL. Pooled analysis of six pharmacologic and nonpharmacologic interventions for vasomotor symptoms. Obstet Gynecol 2015;126(2):413-422. [PMCID: PMC4526122]

Reed SD, Mitchell CM, Joffe H, Cohen L, Shifren JL, Newton KM, Freeman EW, Larson JC, Manson JE, LaCroix AZ, Guthrie KA. Sexual function in women on estradiol or venlafaxine for hot flushes: a randomized controlled trial. Obstet Gynecol 2014;124(2 Pt 1):233-241. [PMCID: PMC4113909]

Ensrud KE, Guthrie KA, Hohensee C, Caan B, Carpenter JS, Freeman EW, LaCroix AZ, Landis CA, Manson J, Newton KM, Otte J, Reed SD, Shifren JL, Sternfeld B, Woods NF, Joffe H. Effects of estradiol and venlafaxine on insomnia symptoms and sleep quality in women with hot flashes. Sleep 2015;38(1):97-108. [PMCID: PMC4262961]

Caan B, LaCroix AZ, Joffe H, Guthrie KA, Larson JC, Carpenter JS, Cohen LS, Freeman EW, Manson JE, Newton K, Reed S, Rexrode K, Shifren J, Sternfeld B, Ensrud K. Effects of estrogen and venlafaxine on menopause-related quality of life in healthy postmenopausal women with hot flashes: a placebo-controlled randomized trial. Menopause 2015:22(6):607-615. [PMCID: PMC4610378]

Diem SJ, Joffe H, Larson JC, Tsai JN, Guthrie KA, LaCroix AZ, Ensrud KE, Freeman EW, Leder BZ. Effects of escitalopram on markers of bone turnover: a randomized clinical trial. J Clin Endocrinol Metab 2014; 99(9):E1732-1737. [PMCID: PMC4154080]

Buchanan DT, Landis CA, Hohensee C, Guthrie KA, Otte JL, Paudel M, Anderson GL, Caan B, Freeman EW, Joffe H, LaCroix AZ, Newton KM, Reed SD, Ensrud KE. Effects of yoga and aerobic exercise on actigraphic sleep parameters in menopausal women with hot flashes. J Clin Sleep Med 2016;13(1):11-18, 2017. [PMCID: PMC5181601]

Oakley AE, Steiner RA, Chavkin C, Clifton DK, Ferrara LK, Reed SD. K Agonists as a novel therapy for menopausal hot flashes. Menopause 2015;22(12):1328-1334. [PMCID: PMC4651855]

Jones SW, Guthrie KA, LaCroix AZ, Sternfeld B, Landis CA, Reed SD, Dunn A, Caan B, Cohen LS, Hunt J, Newton KM. Is heart rate variability associated with frequency and bother of vasomotor symptoms among healthy peri-menopausal and post-menopausal women? Clin Auton Res 2016;26(1):7-13. [PMCID: PMC4742392]

Jones SM, Guthrie KA, Reed SD, Landis CA, Sternfeld B, LaCroix AZ, Dunn A, Burr RL, Newton KM. A yoga & exercise randomized controlled trial for vasomotor symptoms: Effects on heart rate variability. Complement Ther Med 2016;6:66-71. [PMCID: PMC4893767]

McCurry S, Guthrie KA, Morin DM, Woods NF, Landis CA, Ensrud KE, Larson JC, Joffe H, Cohen LS, Hunt JR, Newton KM, Otte JL, Reed SD, Sternfeld B, Tinker LF, LaCroix AZ. Telephone-based cognitive behavioral therapy for insomnia in perimenopausal and postmenopausal women with vasomotor symptoms: a MsFLASH randomized clinical trial. JAMA Intern Med 2016;176(7):913-920. [PMCID: PMC4935624]

Guthrie KA, Larson JC, Ensrud KE, Anderson GL, Carpenter JS, Freeman EW, Joffe, H, LaCroix AZ, Manson JE, Morin CM, Newton KM, Otte J, Reed SD, McCurry S. Effects of pharmacologic and nonpharmacologic interventions on insomnia symptoms and subjective sleep quality in women with hot flashes: A pooled analysis of individual participant data from 4 MsFLASH trials. Sleep 2018:41(1);zsx190. [PMCID: PMC6380606]

Diem SJ, LaCroix AZ. Reed SD, Larson JC, Newton KM, Ensrud KE, Woods NF, Guthrie KA. Effects of pharmacologic and non-pharmacologic interventions on menopause-related quality of life: a pooled analysis of individual participant data from four MsFLASH trials. In press, Menopause 2020.

Carpenter JS, Bakoyannis G, Otte JL, Chen CX, Rand KL, Woods NF, Newton KM, Joffe H, Manson JE, Freeman EW, Guthrie KA. Validity, cut-points, and minimally important differences for two hot flash-related daily interference scales. Menopause 2017;24(8):877-885. [PMCID: PMC6002749]

Mitchell CM, Srinivasan S, Plantinga A, Wu MC, Reed SD, Guthrie KA, LaCroix AZ, Fiedler T, Munch M, Liu C, Hoffman NG, Blair IA, Newton K, Freeman EW, Joffe H, Cohen L, Fredricks DN. Associations between improvement in genitourinary symptoms of menopause and changes in the vaginal ecosystem. Menopause 2018;25(5):500-507. [PMCID: PMC5898977]

Mitchell CM, Reed SD, Diem S, Larson JC, Newton KM, Ensrud KE, LaCroix AZ, Caan B, Guthrie KA. Efficacy of Vaginal Estradiol or Vaginal Moisturizer vs Placebo for Treating Postmenopausal Vulvovaginal Symptoms: A Randomized Clinical Trial. JAMA Intern Med 2018;178(5):681-690. [PMCID: PMC5885275]

Mitchell CM, Reed SD, Guthrie KA. Good clinical practice in diagnosis of vulvovaginal symptoms – Reply. JAMA Intern Med 2018;178(8):1136-1137.

Diem SJ, Guthrie KA, Mitchell CM, Reed SD, Larson JC, Ensrud KE, LaCroix AZ. Effects of vaginal estradiol tablets and moisturizer on menopause-specific quality of life and mood in healthy postmenopausal women with vaginal symptoms: a randomized clinical trial. Menopause 2018;25(10):1086-1093. [PMCID: PMC6136971]

Guthrie KA, Caan B, Diem S, Ensrud KE, Greaves SR, Larson JC, Newton KM, Reed SD, LaCroix AZ. Facebook advertising for recruitment of midlife women with bothersome vaginal symptoms: a pilot study. Clin Trials 2019; 16(5):476-480. [PMCID: PMC6742530]

Mitchell CM, Guthrie KA, Larson J, Diem S, LaCroix AZ, Caan B, Shifren JL, Woods NF, Heiman JR, Lindau S, Reed SD. Sexual frequency and pain in a randomized clinical trial of vaginal estradiol tablets, moisturizer, and placebo in postmenopausal women. Menopause 2019;26(8):816-822. [PMCID: PMC6663586]

Gibson CJ, Huang AJ, Larson JC, Mitchell C, Diem S, LaCroix A, Newton K, Reed S, Guthrie KA. Patient-centered change in the day-to-day impact of postmenopausalmvaginal symptoms: results from a multicentered randomized trial. In press, Am J Obstet Gynecol, 2020.

Hunter MM, Guthrie KA, Larson JC, Reed SD, Mitchell CM, Diem SJ, LaCroix AZ, Huang A. Convergent-Divergent Validity and Correlates of the Day-to-Day Impact of Vaginal Aging Domain Scales in the MsFLASH Vaginal Health Trial. J Sex Med 2020;17(1):117-125. [PMCID: PMC6956841]

Reed SD, LaCroix AZ, Anderson GL, Ensrud KE, Caan B, Carpenter JS, Cohen L, Diem S, Freeman E, Joffe H, Larson JC, McCurry SM, Mitchell CM, Newton KM, Sternfeld S, Guthrie KA. Lights on MsFLASH: a review of contributions. Menopause 2020;27(4):473-484.

Carpenter J, Tisdale J, Chen CX, Kovacs R, Larson J, Guthrie K, Ensrud K, Newton K, LaCroix AZ. A MsFLASH investigation of self-reported menopausal palpitations distress. Submitted, J Womens’ Health, 2020.

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